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Maximum androgen blockade : ウィキペディア英語版
Maximum androgen blockade
Maximum androgen blockade (MAB) or complete or combined androgen blockade (CAB) is a medical treatment involving the combination of both androgen receptor (AR) antagonism and inhibition or suppression of androgen production to attain maximal effectiveness in androgen deprivation therapy. An example of MAB is the combination of bicalutamide, an AR antagonist, with a gonadotropin-releasing hormone (GnRH) GnRH analogue such as leuprorelin or cetrorelix.〔 Cyproterone acetate and galeterone are examples of MAB that combine both mechanisms into a single drug. MAB was developed for and is employed in the treatment of prostate cancer.〔
==References==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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